experimental determination of solubility and ternary phase diagram of chiral compound are of tedious and time consuming tasks, and in many cases, there is not enough experimental data for different enantiomeric compositions to access the experimental ternary phase diagram. using thermodynamic models with predictive capability, having less dependency on experimental data, affords a great advanta...

Experimental determination of solubility and ternary phase diagram of chiral compound are of tedious and time consuming tasks, and in many cases, there is not enough experimental data for different enantiomeric compositions to access the experimental ternary phase diagram. Using thermodynamic models with predictive capability, having less dependency on experimental data, affords a great advanta...

objective(s): the objective of this study was to design a topical microemulsion of vit b12 and to study the correlation between internal structure and physicochemical properties of the microemulsions. microemulsions are thermodynamically stable mixtures of water, oil, surfactants and usually cosurfactants with several advantages for topical and transdermal drug delivery. the formulation of micr...

purpose of this study was to investigate the effect of the presence of the water soluble polymers viz hpmc, pvp and peg 6000 on aqueous solubility and complexation abilities of felodipine with or without presence of β-cyclodextrin (βcd) and hpβcd by phase solubility studies. the data revealed the initial increase in drug solubility followed by plateau in the presence of relatively low polymer c...

the determination region of solubility of methanol with gasoline of high aromatic content was investigated experimentally at temperature of 288.2 k. a type 1 liquid-liquid phase diagram was obtained for this ternary system. these results were correlated simultaneously by the uniquac model. the values of the interaction parameters between each pair of components in the system were obtained for t...

in this study, porous scaffolds from poly(d,l-lactic acid) have been prepared via liquid- liquid phase separation method in ternary system of polymer-1,4-dioxane-water. polymer dissolved in dioxane in 1.5, 2.5 and 5 % wt/v and the solvent/non-solvent ratios were 13/87, 15/85 and 17/83. cloud point curves prepared by visual turbidometry. in order to obtain porous scaffolds with inter-connected p...

abstract: â in this study, the change in the crystalline structure of gas hydrate was predicted for ternary mixture of methane-ethane-water. for this purpose, the tangent plane distance (tpd) minimization method was used. first, the calculations were performed for the binary mixtures of methane-water and ethane-water as the gas and liquid phases. the results show that for a binary mixture of th...

Processing the experimental tie-lines in the miscibility gap of the Ba-Cu-Y ternary liquid alloys coupled with the Gibbs energies of the Ba-Cu and Cu-Y binaries estimated earlier has led to description of the Gibbs energy of the ternary melt and to the complete ternary phase diagram. The transformation of an open triangular simplex to the plane that can ease significantly optimization and calcu...

In this article, the ternary phase diagram in polyamide-6 (PA6)/Formic acid (FA)/Water system was constructed by experimental measurement. The determination of binodal curve was measured according to titration of the PA6 polymer solution with water as a non-solvent until the onset of turbidity. Also, the phase separation process of the prepared membranes structures system was investigated. The ...

In the present work, ternary special quasirandom structures SQSs for a fcc solid solution phase are generated at different compositions, xA=xB=xC= 1 3 and xA= 1 2 , xB=xC= 1 4 , whose correlation functions are satisfactorily close to those of a random fcc solution. The generated SQSs are used to calculate the mixing enthalpy of the fcc phase in the Ca-Sr-Yb system. It is observed that first-pri...